In this episode, Matt answers various questions from viewers of the Optispan Podcast. The conversation covers questions about using compounds like proviron or testosterone gels for women under stress or calorie restriction. Matt advises that any hormone therapy should be done under medical supervision and with regular monitoring of hormone levels.

Regarding testosterone therapy, Matt explains his experience using an injectable testosterone cypionate formulation, administering 0.3 ml twice a week. He tried an oral testosterone product initially but had side effects. Matt provides details on his dosage and injection process

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When asked about the evidence for taking rapamycin in one's 30s, Matt says there is no clear data, but it may be reasonable to try it for certain conditions like autoimmune diseases, Alzheimer's risk, or long COVID, while acknowledging the lack of long-term safety data.

Regarding blood testing while taking multiple supplements, Matt strongly cautions against taking more than 5 supplements, as the interactions become too complex to interpret. He recommends focusing on optimizing a core set of key biomarkers.

The discussion covers the pros and cons of getting full-body DEXA scans versus targeted bone density scans, as well as Matt's own experience with DEXA and his ongoing efforts to reach his body composition goals.

The episode concludes with a discussion of whether protein bars should be considered supplements, Matt's views on the nuances of processed foods, and his experiences enjoying Guinness during a recent trip to Ireland.